Atypical glandular cells of undetermined significance in conventional cervical/vaginal smears and thin-layer preparations

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Atypical glandular cells of undetermined significance on cervical smears. A study with cytohistologic correlation.

OBJECTIVE The incidence of endocervical adenocarcinoma has increased steadily over the past two decades. Since the Bethesda System was introduced, the diagnosis of atypical glandular cells of undetermined significance (AGUS) has also risen and now accounts for 0.46-1.83% of all cervical (Pap) smears. The purpose of this study was to evaluate the significance of a diagnosis of AGUS using cytohis...

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Clinical significance and management of cervical atypical glandular cells of undetermined significance.

OBJECTIVES To assess the clinical significance of a cervical cytological diagnosis of atypical glandular cells of undetermined significance and to formulate the most appropriate management guidelines for patients with such a diagnosis. DESIGN Retrospective study. SETTING Regional hospital, Hong Kong. PATIENTS Seventy-two patients with diagnoses of atypical glandular cells of undetermined ...

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A Comparative Study of Atypical Squamous Cells of Undetermined Significance in Pap Smears Followed by Biopsy Results for Determination of Reliable Cytologic Parameters

  Background and Objective: Microscopic evaluation of cervicovaginal smears (Pap smear) plays an essential role in detection of preneoplastic and neoplastic lesions of uterine cervix. A wide spectrum of changes is seen in Pap smears. Interpretation of intermediate changes which resulting in observation of so- called ASCUS is difficult. ASCUS is defined as a cellular change that is more marked ...

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Cytologic and histologic correlation of atypical glandular cells of undetermined significance.

To determine the cytologic and histologic correlation of atypical glandular cells of undetermined significance (AGUS) in Papanicolaou smears, a cytology file from January 1998 to May 1999 was reviewed. Surgical pathology files were searched to determine which patients received subsequent biopsies. One hundred thirty-two patients with AGUS were identified. Corresponding biopsies were available f...

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Comparison of Diagnostic Cytomorphology of Atypical Squamous Cells in Liquid-Based Preparations and Conventional Smears

BACKGROUND The aims of this study were to compare the cytomorphologic features diagnostic of atypical squamous cells (ASC) in liquid-based preparations (LBPs) and conventional Pap (CP) smears and to cytomorphologically assess the performance of the Cell Scan 1500™ in cervical cytology practice. METHODS Cervicovaginal smears were obtained from 938 women. Two smears were obtained simultaneously...

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ژورنال

عنوان ژورنال: Cancer

سال: 2002

ISSN: 0008-543X

DOI: 10.1002/cncr.10312